We're on the books now, for sure. The surgery date is official, barring some unforeseen surgical bumping... October 22. I'll know the day before what time my lovely cyst will be coming out (heehee).
Got some bad news though at the appointment: both samples sent for fetal genetic karyotyping came back inconclusive (they claim there was no placental/fetal material present in either sample, but my RE begs to differ and is *really* pissed about it since she collected the second sample herself, and another pathologist from a different lab confirmed said sample was indeed placental material.
So we'll never know if my Bug was a carrier of the unbalanced form of the translocation. Sucks.
A little ditty...
This blog is about 'Mrs. Buggy's' journey through infertility: a crushing diagnosis (MFI and b.a.l.a.n.c.e.d. r.e.c.i.p.r.o.c.a.l t.r.a.n.s.l.o.c.a.t.i.o.n.), a miraculous pregnancy despite all odds, only to end in loss at 12w5d, a D&C, laproscopic surgery, and the seemingly never ending wait to undergo IVF, ICSI, and PGS.
Join me for my daily rantings as I try to put a little faith in ART, to have patience with my family and friends, and to navigate the daily bullshit that is infertility.
We've been trying to conceive for over 3 years, and now we're waiting on a February 24 due date after a successful cycle #2 of fertility treatments (IVF with PGS) in June 2011.
Excuse the language and rantings - and remember: infertility causes stress, it's not the other way around.
IVF+PGS Cycle #2
2011
IVF+PGS #2: Short "Flare" Protocol
April: Follow-up appointment to discuss previous cycle attempt
May 3: Appointment to orientate new protocol
May 5: Back on the acupuncture bandwagon
~ Here We Go AGAIN: IVF|ICSI|PGS Cycle #2 ~
May 12: Acupuncture
CD18-24, May 14 - May 20:
Marvelon, once daily for 7 days
CD23, May 19: Acupuncture for both DH & I
CD25, May 21: Start Lupron, 0.2cc, twice daily
CD27, May 23: Add to Lupron:
(am) Menopur 150i.u.
(pm) Bravelle 225i.u.
CD30, May 26: Acupuncture
CD31, May 27: e2 = 317pmol/L
(stim day 5) No changes to doses.
CD34, May 30: e2= 989pmol/L
(stim day 8)
L= 5 follicles measuring 11-13mm; 2 follicles measuring 10mm; 1 cyst 15mm
R= 3 follicles measuring 10-12mm; 1 cyst 21mm
(am)225iu Menopur
(pm)225iu Bravelle
CD36, June 1: e2= 3,182pmol/L
(stim day 10)
L=4 measuring above 17mm
R=2 measuring above 17mm
FUCK! Now we're down to 6?!
CD37, June 2: 10,000iu hCG 'Trigger'; Acupuncture
CD39, June 4: Egg retrieval. 10 eggies! WOOT!
CD40, June 5: Fertilization report - 9 mature; 6 of those fertilized
CD42, June 7: PGS Biopsy Date
CD43, June 8: Acupuncture; HPTs negative - no more trigger in my system
CD44, June 9: Transfer 1 Grade 5BB blast; no frosties; Acupuncture
CD55, June 21: First beta: 496
CD62, June 28: Second beta: 7283
We're Officially Pregnant! HOLY SHITBALLS!
9w0d, July 22: 
FHR=174bpm
FHR=174bpm
10w4d, August 2: BP=112/73 | HR=124bpm
12w3d, August 15: BP=114/70 | HR=122bpm
FHR=160bpm
FHR=160bpm
15w4d, September 6: Midwife Appt. #1
BP=122/66 | HR = 110bpm | total wt. gain = 5lbs
FHR=156bpm
FHR=156bpm
16w5d, September 14: Midwife Appt. #2
BP=124/60 | HR = 108bpm | total wt. gain = 4.5lbs
FHR=150bpm
FHR=150bpm
18w6d, September 29: Fetal Anatomy Scan
21w5d, October 19: Midwife Appt. #3
BP=122/70 | HR = 109bpm | total wt. gain = 10.0lbs
FHR=153bpm
FHR=153bpm
24w3d, November 7: 3D Ultrasound
25w6d, November 17: Midwife Appt. #4
BP=120/74 | HR = 108bpm | total weight gain = 15.2lbs
FHR=148bpm
FHR=148bpm
29w6d, December 15: Midwife Appt. #5
Baby Buggy Girl, born end of February, 2012
The light of our lives is finally here
IVF & PGS Cycle #1
2011
IVF+PGS #1: Long Protocol
Cancelled: Poor Responder
January 27: Another post-op re-check of L. ovary | AFC=13. Protocol Appointment. - Long Protocol
~ Here We Go: IVF|ICSI|PGS Cycle #1 ~
CD1, February 10: Marvelon Day 1
CD14, February 23: Synarel Day 1
CD21, March 2: Last Marvelon
CD24, March 5: Bleed Starts
CD26, March 7:
Bravelle 187.5iu Menopur 75iu
CD29, March 10: E2= 204pmol/L
Bravelle 225iu Menopur 150iu
CD31, March 12: E2= 655pmol/L
5R (2x14mm, 13mm, 11mm, 10mm) 1L
CD33, March 14: E2 = 1764pmol/L
1L (11mm) + 'a few' 10mm or under; confirmed endometrioma
4R (19mm, 18mm, 17mm, 16.5mm) + 'several' 10mm or under
CD34, March 15: E2 =2587pmol/L
Pulling the plug on this cycle:
poor response
Our TTC Timeline - A Bug Odyssey
2009
September: First fertility clinic appointment; Genetic testing requested for DH (karyotyping & Y micro-deletion testing); bloodwork and ultrasound for me (AFC = 13)
October: Results: DH has a balanced r.eciprocal t.ranslocation. Clinic's only option for us is IVF+ICSI+PGD. Told PGD program is in the works and should be up and running by January.
November: Several Geneticist and genetic counselling appointments; miscarriage risk in a natural pregnancy is about 50%; chances of an abnormal (Angel.man's Syn.drome) live birth to term is 10%. Chance of obtaining a natural pregnancy monthly is less than 1% with the MFI and Genetic Factors.
We are devastated.
2010
January: Contacted FC - they're passing me off to one of their competitors - their PGD program won't start for up to a year because of staffing issues. Here we go again.
February: First appointment at new clinic; prelim bloodwork
March 24: Hysterosalpingogram. Normal! Tubes open.
April: Clinic suggests saving some money if we're willing to do amnio given my tubes are open & everything's normal with me & DH's numbers have improved drastically (SPERMIE DIET!!); decide to go ahead with an IUI in May, see what happens.
May 10: Clomid IUI cancelled due to fluke natural BFP
Serial Betas Begin:
July 23: 155 | July 30: 79
July 10: Miscarriage, baby angel at 12w5d
August 5: 58 | August 16: 26
August 27: 14 | September 11: 0
August 19: Sperm sample frozen for ICSI
September 16: Hysteroscopy - retained tissue
September 21: Antral Follicle Count = 14!
September 21: Dilation & Curettage (D&C)
October 2: Fetal karyotype inconclusive on 2 tests.
October 22: Laproscopic Cystectomy - Mucinous cystadenoma
Skipping straight to ICSI/PGD... can't handle the possibility of another miscarriage
November 28: Post-op Appointment; tubes open, normal uterus, no endo present. Bloodwork: (CD5: E2-362pmol/L| FSH-4.6IU/L| Prolactin-9.0ug/L| TSH-2.4mU/L). 2nd hysteroscopy suggested.
December 13: Protocol Appointment Antral Follicle Count = 13; wait on protocol appt. GAH! 2nd hysteroscopy cancelled.
December 22: PGD Consultation Appointment with G.enesis G.enetics, Detroit MI
2011
January 17: Due date of one and only BFP
February 10: Start IVF+PGS Cycle #1, Long Protocol
March 15: Plug pulled on day 9 of stims, over-suppressed
April 6: Follow-up appointment with RE; new protocol discussed (estrogen priming, short protocol)
May 3: Appointment to orientate new protocol
May 21: IVF+PGS Cycle #2 starts
June 9: Transfer 1 genetically normal blast @ 5dpER
June 21: Beta #1, 496
June 28: Beta #2, 7283
July 22: 9weeks, =174bpm
=174bpmGrab my Button
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